hxhgxy.lcu.edu.cn

EMAIL/ dujiyuan@lcu.edu.cn

科研方向/有机化学

教育经历 2008/09-2015/06   兰州大学   博士

2004/09-2008/06   聊城大学   学士

科研项目人

(1)     含芳基取代全碳季碳的氢化吲哚单元不对称构建及在石蒜科生物碱合成中的应用，国家自然科学基金青年项目，2017/01-2019/12。

(2)     “具有全碳季碳中心的氢化吲哚”结构单元的不对称构建及在Crinine类型生物碱合成中的应用，山东省自然科学基金项目，2016/07-2018/07。

获奖情况

论著一览

相关成果

(1)   Ji-Yuan DuU, Chao Zeng, Xiao-Jie Han, Hu Qu, Xian-He Zhao, Xian-Tao An, Chun-An Fan,* Asymmetric Total Synthesis of Apocynaceae Hydrocarbazole Alkaloids (+)-Deethylibophyllidine and (+)-Limaspermidine, J. Am. Chem. Soc. 2015, 137, 4267.

(2)   Fang-Xin Wang, Ji-Yuan Du, Hui-Bin Wang, Peng-Lin Zhang, Guo-Biao Zhang, Ke-Yin Yu, Xiang-Zhi Zhang, Xian-Tao An, Ye-Xing Cao, Chun-An Fan,* Total Synthesis of Lycopodium Alkaloids Palhinine A and Palhinine D, J. Am. Chem. Soc., 2017, 139, 4282.

(3)   Xian-He Zhao, Qing Zhang, Ji-Yuan Du, Xin-Yun Lu, Ye-Xing Cao, Yu-Hua Deng, Chun-An Fan,* Total Synthesis of (±)-Lycojaponicumin D and Lycodoline-Type Lycopodium Alkaloids, J. Am. Chem. Soc., 2017, 139, 7095.

(4)   Xiao-Yan Ma, Xian-Tao An, Xian-He Zhao, Ji-Yuan Du, Yu-Hua Deng, Xiang-Zhi Zhang,  Chun-An Fan,* Au-Catalyzed [2+3] Annulation of Enamides with Propargyl Esters: Total Synthesis of Cephalotaxine and Cephalezomine H, Org. Lett., 2017, 19, 2965.

(5)   Xiang-Zhi Zhang, Ji-Yuan Du, Yu-Hua Deng, Wen-Dao Chu, Xu Yan, Ke-Yin Yu, and Chun-An Fan,* Spirocyclopropanation Reaction of para-Quinone Methides with Sulfonium Salts: The Synthesis of Spirocyclopropanyl para-Dienones, J. Org. Chem., 2016, 81, 2598.

(6)  Cong-Yang Jin, UJi-Yuan DuU, Chao Zeng, Xian-He Zhao, Ye-Xing Cao, Xiang-Zhi Zhang, Xin-Yun Lu, Chun-An Fan,* Hypervalent Iodine(III)-Mediated Oxidative Dearomatizing Cyclization of Arylamines, Adv. Synth. Catal. 2014, 356, 2437.

(7)  Xu Bao, Ye-Xing Cao, Wen-Dao Chu, Hu Qu, UJi-Yuan DuU, Xian-He Zhao, Xiao-Yan Ma, Cheng-Tao Wang, Chun-An Fan,* Bioinspired Total Synthesis of Montanine-Type Amaryllidaceae Alkaloids, Angew. Chem., Int. Ed. 2013, 52, 14167.

(8)  Wen-Dao Chu, Le-Fen Zhang, Xu Bao, Xian-He Zhao, Chao Zeng, Ji-Yuan Du, Guo-Biao Zhang, Fang-Xin Wang, Xiao-Yan Ma, Chun-An Fan,* Asymmetric Catalytic 1,6-Conjugate Addition/Aromatization of para-Quinone Methides: Enantioselective Introduction of Functionalized Diarylmethine Stereogenic Centers, Angew. Chem., Int. Ed, 2013, 52, 9929.

(9)  Meng-Xue Wei, Cheng-Tao Wang, Ji-Yuan Du, Hu Qu, Pei-R ong Yin, Xu Bao, Xiao-Yan Ma, Xian-He Zhao, Guo-Biao Zhang, Chun-An Fan,* Enantioselective Synthesis of Amaryllidaceae Alkaloids (+)-Vittatine, (+)-epi-Vittatine, and (+)-Buphanisine, Chemistry – An Asian Journal, 2013, 8, 1966.

(10) Jing Li, Guo-Liang Liu, Xian-He Zhao, Ji-Yuan Du, Hu Qu, Wen-Dao Chu, Ming Ding, Cong-Yang Jin, Meng-Xue Wei, Chun-An Fan,* Formal Synthesis of (±)-Morphine, Chemistry – An Asian Journal, 2013, 8, 1105.

(11) Guo-Biao Zhang, Fang-Xin Wang, UJi-Yuan DuU, Hu Qu, Xiao-Yan Ma, Meng-Xue Wei, Cheng-Tao Wang, Qiong Li, and Chun-An Fan,* Toward the Total Synthesis of Palhinine A: Expedient Assembly of Multifunctionalized Isotwistane Ring System with Contiguous Quaternary Stereocenters, Org. Lett. 2012, 14, 3696.

(12) Jian-Dong Liu, Ying-Chun Chen, Guo-Biao Zhang, Zhi-Qiang Li, Peng Chen, Ji-Yuan Du, Yong-Qiang Tu, Chun-An Fan,* Asymmetric Organocatalytic Intramolecular Aza-Michael Addition of Enone Carbamates: Catalytic Enantioselective Access to Functionalized 2-Substituted Piperidines, Adv. Synth. Catal. 2011, 353, 2721.